Publications by authors named "I Daniel"
Ferroptosis is linked to various tumor biological traits, and alternative splicing (AS), a crucial step in mRNA processing, plays a role in the post-transcriptional regulation of ferroptosis-related genes (FRGs). A least absolute shrinkage and selection operator (LASSO) penalized Cox regression analysis was utilized to build a prognostic signature based on 12 AS events (p < 0.05), which was validated in gastric cancer (GC) patients.
View Article and Find Full Text PDFEntomopathogenic fungi (EPFs) can infect and kill a diverse range of arthropods, including ticks (Acari: Ixodidae) that can transmit various diseases to animals and humans. Consequently, the use of EPFs as a biocontrol method for managing tick populations has been explored as an alternative to chemical acaricides, which may have harmful effects on the environment and non-target species. This review summarizes studies conducted on EPFs for tick control between 1998 and 2024, identifying 9 different EPF species that have been used against 15 different species of ticks.
View Article and Find Full Text PDFBackground: In Tanzania, acute myocardial infarction (AMI) is under-diagnosed, and uptake of evidence-based care is sub-optimal. Using an implementation science approach, an intervention was developed to address local barriers to care: the Multicomponent Intervention for Improving Myocardial Infarction Care in Tanzania (MIMIC).
Methods: This single-arm pre-post trial was conducted in a northern Tanzanian emergency department (ED).
The association of ABC proteins with multidrug resistance in cancer.
Biochim Biophys Acta Mol Cell Res
February 2025
Article Synopsis
- Multidrug resistance (MDR) in cancer treatment, particularly for metastatic disease, is largely driven by the overexpression of ATP-binding cassette (ABC) proteins.
- A total of 20 ABC proteins were identified as associated with MDR, highlighting the importance of drug transport and sequestration within cells.
- The study emphasizes the need for further research to understand MDR mechanisms better and improve pharmacological approaches for more effective cancer treatments.
Knowledge production as an enabler to effective organisational resilience.
J Bus Contin Emer Plan
January 2025
Article Synopsis
- - Organisational resilience relies on effective knowledge-driven standards and practices that help risk owners manage complex threats, making knowledge essential for developing resilience strategies.
- - Knowledge production can evolve through opportunistic or structured methods, promoting transformative or incremental change, and fosters collaboration among security professionals to identify and address skill gaps.
- - The paper discusses the role of security professionals, the creation and application of knowledge, the significance of training and credible resources, and the necessity for a recognized competency framework to guide professional development in the security field.