Implementing National Guidelines in Real Life: The Peterborough Neurodevelopmental Service (NDS).

National documents over the last few years have highlighted the mental health needs of children with neurodevelopmental disabilities. Results showed the poor levels of provision for this vulnerable high-risk group. The National Service Framework (NSF) for children, (DoH, 2004), set out 9 standards for care and service development.

A multicentre comparison of the efficacy of terbutaline Turbuhaler and salbutamol pressurized metered dose inhaler in hot, humid regions.

Twenty seven adults and 20 children with previously diagnosed stable asthma, using a salbutamol pressurized metered dose inhaler (P-MDI) and living in Cairns, Townsville and Southport, Queensland, Australia participated in a randomized, open-label cross-over comparison of terbutaline administered via Turbuhaler and salbutamol administered via P-MDI. The aim of the study was to compare the clinical effectiveness and patient acceptance of the two treatments in hot, humid regions. Terbutaline was administered via Turbuhaler and salbutamol via P-MDI on at least two occasions per day during each four week treatment period.

Gliosis and aqueductule formation in the aqueduct of Sylvius.

A study was made of the cerebral aqueducts of 30 children with hydrocephalus but without myelomeningocele. A sequence of events is demonstrated which suggests a mechanism of aqueductule formation and burial of ependymal cells. The cellularity of areas of gliosis may normally decrease and resemble normal neural tissue, but occasionally activity is perpetuated by continuing irritants.

Unwanted corticosteroid effects in childhood bone marrow failure, renal failure and brain damage: case report.

The case report of the corticosteroid complication in an eight-year-old girl with immune thrombocytopenic purpura is presented. She was treated with high dosage corticosteroids and incurred severe side effects, including bone marrow depression, renal magnesium stones, osteoporosis, depression of affect, convulsions with cerebral damage and adrenal suppression.