Publications by authors named "I D Sham'yanov"

In continuation of our phytochemical study on the aerial part of (Kovalevsk.) Kovalevsk, three new guaiane-type sesquiterpene lactones were isolated namely karatanolide (), 11,13-dihydrokaratanolide () and 11,13-dihydrokaratanolide (), in addition to the two known sesquiterpene lactones 1,10-dihydroxyarglabin () and artefin (). The structures of the isolated sesquiterpene lactones were elucidated by IR and NMR spectroscopy.

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Article Synopsis
  • Two sesquiterpene lactones, 1 ,10,3,4-diepoxyguai-5,6,7-11(13)-en-6,12-olide and hanphyllin, were isolated from the plant Kovalevsk and characterized using advanced techniques like HR-ESI-MS, IR, and NMR.
  • The X-ray diffraction analysis provided precise spatial structures of both compounds.
  • The chloroform fraction containing these compounds showed stronger cytotoxic effects on HeLa (89.7%) and HEp-2 (63.0%) cancer cells compared to individual compounds and cisplatin, while being less toxic to liver cells.
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The title compound, C18H16O8, was isolated from the plant Artemisia baldshuanica Krasch et Zarp. The mol-ecule is approximately planar, with the exception of the terminal methyl groups, the C atoms of which devitate from their attached ring planes by 1.243 (5) and 1.

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