Observation-constrained projections reveal longer-than-expected dry spells.

Climate models indicate that dry extremes will be exacerbated in many regions of the world. However, confidence in the magnitude and timing of these projected changes remains low, leaving societies largely unprepared. Here we show that constraining model projections with observations using a newly proposed emergent constraint (EC) reduces the uncertainty in predictions of a core drought indicator, the longest annual dry spell (LAD), by 10-26% globally.

On non-trivial hyperbolic sets and their bifurcations in families of diffeomorphisms of a two-dimensional torus.

We propose a simple model-two-parameter family of diffeomorphisms of a two-dimensional torus. Combining analytical and numerical methods, we find regions in the parameter plane such that each diffeomorphism of the family is hyperbolic and describe the structure of the corresponding hyperbolic sets. We also study bifurcations on the boundaries of these regions, which lead to the change of hyperbolicity type (from Anosov diffeomorphisms to DA-diffeomorphisms).

Spiroconjugated 1,2,3-triazolo[5,1-]1,3,4-thiadiazine stimulates functional activity of fibroblasts under skin injury regeneration.

Background And Purpose: One of the most important mechanisms of tissue regeneration is the high functional activity of cells, including proliferation. Currently, there are practically no effective skin cell activators on the pharmaceutical market. The purpose of this work was to demonstrate the stimulating effect of spiroconjugated 1,2,3-triazolo[5,1-]1,3,4-thiadiazine (STT) on the functional activity of fibroblasts.

Caregivers' experience of caring for family members with complex health needs in Latvia.

The article examines the experiences of family caregivers engaged in the provision of long-term care for their relatives with complex health needs within the Latvian context. Semi-structured interviews were conducted with seven caregivers who provide care in cases of dementia, depression, schizophrenia, opioid use, Down syndrome and mild cognitive impairment. A thematic analysis of interview transcripts revealed common themes, such as the initial experiences when encountering a family member's disorder and the subsequent reactions, as well as the quest for support and resources.

The structure and behavioral patterns of the human population affected by ixodid tick bites in Irkutsk Region, Eastern Siberia, Russia.

The bites of hard ticks are the major route of transmission of tick-borne infections to humans, causing thousands of cases of diseases worldwide. However, the characteristics of the human population that is exposed to tick bites are still understudied. This work is aimed at characterizing both the structure of the population directly contacting ticks and the human behavioral features associated with tick bites.