[Vaginosis in patients with antenatal foetus death].

Polymerase chain reaction (PCR) analysis of bacterial vaginosis as well as of vaginal anaerobe flora (Mycoplasma Hominis, Ureaplasma urealyticum, Gardnerella vaginalis, Bacteroides spp. and Mobiluncus curtisii) was performed in women with antenatal foetus death. Specimens from forty women with this pathology were studied.

[Effect of the calcitonine gene-related peptide on the myometrium contractile activity].

It is known that in the processes of contraction, as well as of relaxation of the myometrium, besides widely accepted regulatory mechanisms, such as steroid hormones, also participate catecholamine, oxytocine and prostaglandine, and other substances of peptide nature. In particular one of such compounds was studied in the present investigation. This compound is known as the peptide connected to the calcitonine gene (CGRP), whose role in the contractile activity of the myometrium is very significant.

[Molecular mechanisms of regulation uterine contractile activity during pregnancy and labor in mammals].

Main purpose of the investigation was to study basic mechanisms of regulation uterine contractile activity on various stages of gestation, labor and to determine nature of substances activating, inhibiting and modulating myometrium contractility. The study was carried out on 115 pregnant and not pregnant women, and women in labor, and on 45 newborns. The experiments analyzed hypothalamus and uterus of 100 white rats and brain of 45 newborn rats.

[Infectious causes of intrauterine fetal death].

We have done retrospective analysis of stillbirth. The aim of our study was to investigate specific role of infections in stillbirth on the basis of archival data of Acad. Chachava Research Institute of Perinatal Medicine, Obstetrics and Gynecology.

Role of intracellular infections in premature childbirth.

Vaginal Smear taken by sterile Folkman spoon from 15 women with premature birth was studied. The study was performed by the direct immune fluorescence method with the luminescence microscope. We aimed to study the effect of intracellular infections: ureaplasma urealitikum, mycoplasma hominis, Chlamydia trachomatis, herpes simplex virus of I and II type and cytomegalovirus.