[Morphological changes of testicular tissues in rats of different age groups, depending on the time of being in the abdominal cavity].

Pathological changes in the testes of animals of different age groups with the experimentally simulated cryptorchidism were evaluated. Animals were divided into 3 groups according to the time of fixation of testes into the abdominal cavity for a term of 2, 3 and 4 weeks. The changes were recorded at the time of bringing down the testes into the scrotum and at 14th and 28th day after bringing down.

[Transplantation of hormone-producing cells into the testicular paravasal fat hole in secretory infertility and gonadal hypoplasia].

Intratesticular cell transplantation is an effective surgical method in the treatment of patients with secretory infertility in chronic orchoepididymitis accompanied and not accompanied with marked testicular hypoplasia. This treatment in patients with secretory infertility and testicular hypoplasia enlarges gonads by more than 60% (from 3 to 5 mm3). The density of spermatozoa on the spermogram of males both with and without testicular hypoplasia increased by more than 70%--from 7.

[Allotransplantation of testicle in clinical practice. Part 2].

Long-term results of 90 allotransplantations of vascularized testicle are analyzed. The operations were performed at the patients with primary hypogonadism, androgenic deficient and endocrine form of impotence. Maximal follow-up period is 21 years.

[Allotransplantation of testicle].

Allotransplantation of vascularized testicle with mild immune suppression was performed at 132 patients with primary hypogonadism associated with androgenic deficient and endocrine form of impotence. This method permits to achieve stable engraftment in early postoperative period at 83% patients. Acute immunologic rejection crisis and secondary wound disruption are the most frequent complications at early postoperative period.

[Male infertility in delay of sexual development].

The examination of 260 infertile males revealed that delay of sexual development (DSD) predisposes to male infertility. DSD is often characterized by autoimmune reactions pointing to DSD as one of the causes of autoimmune infertility. Spermatozoa in DSD have low viability.