Enhancing tomato (Solanum lycopersicum) yield and nutrition quality through hydroponic cultivation with treated wastewater.

Utilizing treated wastewater for crop cultivation is essential in regions with scarce freshwater resources for irrigation. This study evaluated the growth, fruit yield, nutritional and phytochemical quality of tomato fruits cultivated using a treated wastewater-based hydroponics system developed for the Trans Himalaya, India. Tomatoes grown with treated wastewater exhibited better growth, yield, nutritional content, phytochemical properties, and antioxidant activities than those grown in soil.

Tailored NADES solvents for the extraction optimization of benzylisoquinoline alkaloids from Thalictrum foliolosum DC.- A potential phyto-nutraceutical source.

From a perspective focused on phyto-nutraceuticals, alkaloids are considered to be the most significant metabolites, as they exhibit a broad range of pharmacological applications. Therefore, it is essential, to conduct a thorough investigation of the extraction techniques employed and to optimize the overall process. Considering this, we delved into tailor-made natural deep eutectic solvents coupled with ultrasonic-assisted extraction and macroporous resins aided recovery of therapeutics alkaloids from Thalictrum foliolosum DC.

DNA Methylation Patterns Associated with Tinnitus in Young Adults-A Pilot Study.

Purpose: Tinnitus, the perception of sound without any external sound source, is a prevalent hearing health concern. Mounting evidence suggests that a confluence of genetic, environmental, and lifestyle factors can influence the pathogenesis of tinnitus. We hypothesized that alteration in DNA methylation, an epigenetic modification that occurs at cytosines of cytosine-phosphate-guanine (CpG) dinucleotide sites, where a methyl group from S-adenyl methionine gets transferred to the fifth carbon of the cytosine, could contribute to tinnitus.

Investigating the Potential of 2-Ethylbutyl-(Phenoxy)phosphoryl-D-Alaninate Against RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2.

There was an emergency call globally when COVID-19 was detected in December 2019. The SARS-CoV-2 virus, a modified virus, causes this contagious disease. Although research is being conducted throughout the world, the main target is still to find the promising candidate to target RNA-dependent RNA polymerase (RdRp) to provide possible drug against COVID-19.

A genome-wide association study reveals a polygenic architecture of speech-in-noise deficits in individuals with self-reported normal hearing.

Speech-in-noise (SIN) perception is a primary complaint of individuals with audiometric hearing loss. SIN performance varies drastically, even among individuals with normal hearing. The present genome-wide association study (GWAS) investigated the genetic basis of SIN deficits in individuals with self-reported normal hearing in quiet situations.