Publications by authors named "I Cocchi"
Article Synopsis
- Children with perinatally acquired HIV (PHIV) have unique vaccination needs due to their less effective immune responses compared to healthy controls (HCs).
- A study evaluated the safety and effectiveness of a meningococcal vaccine in both PHIV-affected children and HCs, finding that while the vaccine was safe for both groups, PHIV showed lower immune responses.
- Further analysis revealed differences in B cell behavior and gene expression between PHIV children and HCs post-vaccination, indicating that PHIV may have different mechanisms affecting long-term immunity, warranting more research in these vulnerable groups.
Background: Limited data are currently available on the incidence rates and risk factors for bacterial sepsis and invasive fungal infections (IFIs) among neonates and infants undergoing major surgery.
Aim: To assess the incidence of bacterial sepsis and IFI, fungal colonization, risk factors for sepsis, and mortality in neonates and infants aged <3 months undergoing major surgery.
Methods: A multicentre prospective study was conducted involving 13 level-3 neonatal intensive care units in Italy, enrolling all infants aged ≤3 months undergoing major surgery.
Brain injury at birth is an important cause of neurological and behavioral disorders. Hypoxic-ischemic encephalopathy (HIE) is a critical cerebral event occurring acutely or chronically at birth with high mortality and morbidity in newborns. Therapeutic strategies for the prevention of brain damage are still unknown, and the only medical intervention for newborns with moderate-to-severe HIE is therapeutic hypothermia (TH).
View Article and Find Full Text PDFBackground: Patients with Parkinson's disease (PD) suffer from postural disorders. This study aims at investigating the short- and medium-term effects of a shirt with appropriate tie-rods that allows to correct the posture of the trunk.
Methods: This is a longitudinal clinical study in which a pressure platform was used to assess the static and dynamic baropodometry and the static stabilometry of 20 patients with PD (70.