Publications by authors named "I Chang Hsieh"

Background: Few studies have incorporated echocardiography and laboratory data to predict clinical outcomes in heart failure with preserved ejection fraction (HFpEF).

Objectives: This study aimed to use machine learning to find predictors of heart failure (HF) hospitalization and cardiovascular (CV) death in HFpEF.

Methods: From the Chang Gung Research Database in Taiwan, 6,092 HFpEF patients (2,898 derivation, 3,194 validation) identified between 2008 and 2017 were followed until 2019.

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Background: Dual antiplatelet therapy (DAPT) is the standard treatment for acute myocardial infarction (MI). This study aimed to investigate the use of DAPT and de-escalation after discharge in real-world practice among patients with acute MI undergoing percutaneous coronary intervention (PCI) in Taiwan.

Methods: Using the Taiwan National Health Insurance Research Database, we included patients who received PCI for acute MI and survived to discharge with DAPT from 2011 to 2021.

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Objective: Hemodynamic monitoring via right heart catheterization (RHC) is critical for managing acute coronary syndrome (ACS) patients with heart failure or cardiogenic shock. However, the prognostic value of RHC-derived hemodynamic indices in ACS patients with left ventricular systolic dysfunction (LVSD) but without heart failure or shock remains uncertain.

Methods: A retrospective cohort study included 1151 consecutive ACS patients who underwent RHC during hospitalization from 2007 to 2016.

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Article Synopsis
  • The study examined trends in controlling low-density lipoprotein cholesterol (LDL-C) and the use of lipid-lowering drugs among Taiwanese patients with atherosclerotic cardiovascular disease (ASCVD).
  • Data was collected from the T-SPARCLE Registry, categorizing ASCVD patients based on their medical history, and analyzed LDL-C levels from 2015-2020 along with therapy patterns.
  • Results showed an increase in lipids-lowering drug use, but over 60% of patients still did not meet LDL-C targets, highlighting gaps in following treatment guidelines, particularly for those with acute coronary syndrome or prior interventions.
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