Publications by authors named "I Cha"
During the study of microbial diversity of forest soil in the Republic of Korea, a yellow pigment-producing, Gram-stain-negative, rod-shaped, motile bacterium was isolated and designated as strain 1W2. This strain grew at temperature of 10-37 °C, at pH of 5.0-9.
View Article and Find Full Text PDFAltered gut microbiome in convalescent patients with coronavirus disease 2019.
Front Cell Infect Microbiol
December 2024
Introduction: Coronavirus disease 2019 (COVID-19) alters the gut microbiome. This study aimed to assess the association between the disease severity of COVID-19 and changes in stool microbes through a seven-month follow-up of stool collection.
Methods: We conducted a multicentre, prospective longitudinal study of 58 COVID-19 patients and 116 uninfected controls.
Clinical and Radiographic Features of Peri-Implant Medication-Related Osteonecrosis of the Jaw: A Retrospective Study.
Clin Implant Dent Relat Res
November 2024
Introduction: This study aimed to analyze the factors affecting the occurrence of peri-implant medication-related osteonecrosis of the jaw (PI-MRONJ) in patients using anti-resorptive drugs (ARDs) on different implant position, inclinations, and types of prosthesis.
Methods: The data of 75 patients with bone necrosis that progressed around the implant between 2018 and 2022 were retrospectively examined to identify the factors influencing PI-MRONJ. Data, including patient demographics (age, sex, smoking status, concomitant disease, time of ARD therapy, dose of ARDs, and parafunctional habits) and implant-specific information (type of prosthesis, angle of insertion), were extracted from medical and dental records.
Article Synopsis
- A new archaeon named MBLA0158 was discovered in a solar saltern in Korea, characterized by its red pigmentation and ability to thrive in highly saline environments.
- * The strain grows best at temperatures of 37°C and in 20% salt concentration, and molecular analysis shows it is closely related to Halobellus inordinatus with 96% genetic similarity.
- * It is proposed as a new species, Halobellus rubicundus sp. nov., based on unique genetic features and a distinct genomic profile.
Article Synopsis
- Kaposi's sarcoma-associated herpesvirus (KSHV) is responsible for diseases like Kaposi's Sarcoma and has a high prevalence in sub-Saharan Africa, making vaccine development critical, but existing challenges include the absence of viable animal models for KSHV infection.
- The study created a chimeric mouse virus (MHV68-K-K8.1) to mimic KSHV infection and tested two K8.1 vaccines (mRNA-LNP and Ferritin nanoparticles) which successfully stimulated immune responses in mice.
- Results showed that mice vaccinated with K8.1 mRNA LNP vaccines had reduced viral levels and reactivation rates of the surrogate virus, indicating the potential effectiveness of these