PET-adapted therapy after three cycles of ABVD for all stages of Hodgkin lymphoma: results of the GATLA LH-05 trial.

The role of Ann Arbor staging in determining treatment intensity after achieving a negative positron emission tomography (PET) has not been established in classical Hodgkin lymphoma (cHL). Patients with stage I-IV cHL, received three cycles of ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) and an interim PET scan (PET3). PET3-negative patients received no further therapy.

Dynamic switching of a packaged photonic integrated network-on-chip using an FPGA controller.

A packaged photonic integrated network-on-chip (NoC) based on multi-microrings with a controller and scheduler implemented in FPGA is demonstrated under dynamic packet-switched traffic. Multiple transmission scenarios have been investigated, comprising up to three interfering signals at the same wavelength. The dynamic switching exhibits a power penalty of approximately 0.

Experimental demonstration of a 24-port packaged multi-microring network-on-chip in silicon photonic platform.

A 24-port packaged multi-microring optical network-on-chip has been tested for simultaneous co- and counter-propagating transmissions at the same wavelength at 10 Gbps. In the co-propagating scenario communications up to five hops with one interfering signal have been tested, together with transmissions impaired by up to three interfering signals. In the counter-propagating scenario the device performance has been investigated exploiting the ring resonators in both shared-source and shared-destination configurations.

BER evaluation of a low-crosstalk silicon integrated multi-microring network-on-chip.

The operation of an integrated silicon-photonics multi-microring network-on-chip (NoC) is experimentally demonstrated in terms of transmission spectra and bit error rates at 10 Gb/s. The integrated NoC consists of 8 thermally tuned microrings coupled to a central ring. The switching functionalities are tested with concurrent transmissions at both the same and different wavelengths.

Silicon-based all-optical multi microring network-on-chip.

An optical multi microring network-on-chip (MMR NoC) is proposed and evaluated through numerical simulations. The network architecture consists of a central resonating microring with local microrings connected to the input/output ports. A mathematical model based on the transfer matrix method is used to assess the MMR NoC performance and to analyze the fabrication tolerances.