Publications by authors named "I Ceausu"
Objective: Omentum involvement resulting from uterine perforation is a rare complication following intrauterine procedures that might require immediate intervention due to severe ischemic consequences. This review examines the prevalence of this complication, risk factors, the mode and timing of diagnosis, the proper management and the outcome.
Methods: A systematic literature search was conducted on PubMed, PubMed Central and Scopus using uterine perforation, D&C, abortion and omentum as keywords.
Introduction: There is increasing evidence that vitamin D has widespread tissue effects. In addition to osteoporosis, vitamin D deficiency has been associated with cardiovascular disease, diabetes, cancer, infections and neurodegenerative disease. However, the effect of vitamin D supplementation on non-skeletal outcomes requires clarification, especially in postmenopausal women.
View Article and Find Full Text PDFGestational diabetes mellitus (GDM) is a metabolic complication of pregnancy. The pathogenesis of GDM is considered to involve β-cell dysfunction and insulin resistance (IR). GDM is associated with a significant risk of macrosomia in addition to a high probability of metabolic complications for the offspring.
View Article and Find Full Text PDFArticle Synopsis
- Exosomes, small vesicles that carry proteins reflecting their cell of origin, were studied in the context of gestational diabetes mellitus (GDM), which features low-grade inflammation and vascular issues.
- In a study involving 18 pregnant women (8 controls and 10 GDM patients), blood samples were analyzed to determine changes in exosomal proteins using mass spectrometry and correlations with clinical parameters.
- The analysis identified 78 proteins with significant changes in GDM, including alterations in complement and coagulation proteins, suggesting potential insights into GDM's underlying mechanisms and their clinical relevance.
Background: Neurogenic detrusor overactivity (NDO) is treated with antimuscarinics as first-line treatment. For patients with contraindications or unresponsive, intradetrusor injections with botulinum toxin (BoNT) are a safe and effective but expensive option.
Study Question: Our study evaluated whether adding solifenacin to the intradetrusor injection of BoNT A could boost the effect of BoNT in patients with NDO due to multiple sclerosis or spinal cord injury refractory to antimuscarinics alone and/or lead to less frequent injections.