Publications by authors named "I Cardoso"

The Pasiphaeidae Dana, 1852 are a marine shrimp family occurring in both shallow and deeper waters, with its greatest diversity occurring in tropical and subtropical deep seas. This family includes seven genera and 104 species, and is globally distributed. Currently, the genus Pasiphaea Savigny, 1816 includes 73 species, seven of them recorded in the southwestern Atlantic.

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Exposure to environmentally relevant levels of settleable atmospheric particulate matter (SePM) limits the aerobic performance of inactive healthy adult fish. We evaluated the gill morpho-functional impacts (gill structure and ionic balance) caused by SePM exposure (96 h) in Nile tilapia when fish is impelled to maximal aerobic swimming effort. In control fish, swimming reduced epithelial filament thickness (EFT, 25 %), increased the distance between lamellae (DL, 21 %), and reduced the plasma Na (5 %).

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Germ cell tumors (GCTs) constitute diverse neoplasms arising in the gonads or extragonadal locations. Testicular GCTs (TGCTs) are the predominant solid tumors in adolescents and young men. Despite cisplatin serving as the primary therapeutic intervention for TGCTs, 10‑20% of patients with advanced disease demonstrate resistance to cisplatin‑based chemotherapy, and epithelial‑mesenchymal transition (EMT) is a potential contributor to this resistance.

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Sugars (saccharides) are sweet-tasting carbohydrates that are abundant in foods and play very important roles in living organisms, particularly as sources and stores of energy, and as structural elements in cellular membranes. They are desirable therapeutic targets, as they participate in multiple metabolic processes as fundamental elements. However, the physicochemical characterization of sugars is a challenging task, mostly due to the structural similarity shared by the large diversity of compounds of this family.

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Article Synopsis
  • - Tau is a disordered protein linked to neurodegenerative diseases, forming aggregates in the brain, and researchers are trying to understand its self-assembly process in the lab.
  • - The Tau AD core fragment (TADC) is a promising model for studying tau aggregation without using cofactors, and it successfully forms fibrils when incubated at 37 °C.
  • - Using various amyloid-binding fluorophores, the study measures TADC aggregation, discovering that while most dyes can detect its species, only three effectively tracked different aggregation rates, indicating varied species presence.
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