Publications by authors named "I C Robinson"
The Impact of Bolus Rheology on Physiological Swallowing Parameters Derived by Pharyngeal High-Resolution Manometry Impedance.
Neurogastroenterol Motil
December 2024
Article Synopsis
- The study examines how the rheology (flow behavior) of ingested fluids affects swallowing and the physiological responses during deglutition, specifically comparing xanthan gum (XG) and sodium carboxymethylcellulose gum (CMC) in healthy adults.
- Results showed that CMC had significantly higher viscosity than XG at higher shear rates (300 s), leading to increased flow resistance during swallowing, indicated by higher intrabolus pressure and altered relaxation times of the upper esophageal sphincter (UES).
- The findings suggest that the differences in shear viscosity of these fluids affect pharyngeal function during swallowing, highlighting the importance of fluid properties over standardized viscosity levels (IDDSI).
While primarily observed in adults, this case contributes valuable insights into the manifestation and management of this benign salivary gland tumor within the pediatric population. This paper reports the first documented case of sinonasal pleomorphic adenoma in pediatric otolaryngology, presenting a unique perspective on this rare nasal tumor in a 9-year-old boy. The patient presented with progressive nasal obstruction and epistaxis and underwent a smooth endoscopic resection of a 2-cm pleomorphic adenoma on the right anterior nasal septum.
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- - Molecular Dynamics (MD) simulations help us understand how biomolecules change shape and interact, which is crucial for insights into their behavior and drug interactions.
- - There's a need for an open access repository for storing and sharing these simulations, as currently, they are scattered and lack a consistent organization.
- - MDRepo is introduced as a solution, offering a standardized way to contribute, analyze, and visualize MD simulations, built on the CyVerse infrastructure to handle large amounts of data efficiently.
Background: Cervical cytology is recommended by WHO as a triage option in HPV-based cervical cancer screening programmes. We assessed the performance of cytology to detect CIN3+ without and with knowledge of HPV positivity.
Methods: Women were screened with cytology and HPV across ESTAMPA study centres in Latin America.