Publications by authors named "I C Ndiaye"
Article Synopsis
- Acinetobacter baumannii, especially the carbapenem-resistant strains (CRAB), is a critical pathogen linked to antimicrobial resistance (AMR) and is prioritized by the WHO.
- Phage therapy is being explored as a potential treatment for CRAB infections due to increasing resistance to conventional antibiotics.
- A newly isolated lytic phage, vAbaIN10, exhibits effective lytic activity against CRAB in various conditions and shows promise in advancing treatment options for multidrug-resistant infections.
Background and objectives Antimicrobial resistance (AMR) is a growing global threat, with carbapenemase-producing Enterobacterales (CPEs) representing a critical public health challenge. Rapid and accurate detection of CPEs is essential for controlling fatal bacterial AMR infections. This study evaluated the performance of MacConkey media supplemented with ertapenem (MacErt1 and MacErt2) for the detection of CPEs.
View Article and Find Full Text PDFArticle Synopsis
- Extended-spectrum β-lactamase-producing (ESBL-) bacteria are a major public health issue due to their widespread resistance to multiple antibiotics, particularly among broiler chickens in Dakar, Senegal.
- A study found that 61.7% of broilers carried ESBL- in their cecum, with antibiotic tests revealing high resistance rates to various β-lactam antibiotics but full susceptibility to imipenem.
- The research indicates significant multidrug resistance and the presence of multiple ESBL genes, highlighting the risk of human transmission through the food supply and the need for better surveillance and intervention strategies.
Article Synopsis
- * In this study, two bacteriophages, vAbBal23 and vAbAbd25, were isolated from wastewater in Dakar, Senegal, and extensively characterized for their effectiveness against extremely drug-resistant strains of A. baumannii.
- * Both phages showed strong antibacterial properties across various pH levels and temperatures, with the ability to attack both active and biofilm forms of the bacteria, indicating their potential as safe therapeutic agents devoid of harmful genes.
Background: Measuring malaria transmission intensity using the traditional entomological inoculation rate is difficult. Antibody responses to mosquito salivary proteins like SG6 have been used as biomarkers of exposure to Anopheles mosquito bites. Here, we investigate four mosquito salivary proteins as potential biomarkers of human exposure to mosquitoes infected with P.
View Article and Find Full Text PDF