Publications by authors named "I C Cunha-Ferreira"
The biotechnological industry faces a crucial demand for novel bioactive compounds, particularly antimicrobial agents, to address the rising challenge of bacterial resistance to current available antibiotics. Traditional strategies for cultivating naturally occurring microorganisms often limit the discovery of novel antimicrobial producers. This study presents a protocol for targeted selection of bacterial strains using the supernatant of , which produces abundant signal molecules and antimicrobial peptides.
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- - A new bacterial strain, identified as Comamonas sp., has been isolated from the Brazilian Cerrado biome and is classified as a novel species within the Comamonas genus, proposed to be named Comamonas brasiliensis nov.
- - Genetic analyses, including dDDH and ANI, suggested that this strain has a close relationship with Comamonas testosteroni but is distinct enough to be considered a separate species.
- - The strain is characterized as a Gram-negative, non-spore-forming, motile bacterium, with optimal growth conditions at 30°C and a pH range of 5-8, along with unique fatty acid profiles related to its metabolism.
An Actinobacteria - Kitasatospora sp. K002 - was isolated from the soil of Cerrado, a savanna-like Brazilian biome. Herein, we conducted a phylogenetic, phenotypic and physiological characterization, revealing its potential for biotechnological applications.
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- Sponges from South America and Antarctica are closely related but have distinct microbiomes, which this study aimed to explore.
- A total of 71 sponge samples were analyzed using advanced sequencing techniques, revealing that most symbionts were heterotrophic and dominated by Proteobacteria and Bacteroidota.
- The study found significant differences in microorganism abundance between the regions, with South American sponges having more photosynthetic microbes and Antarctic sponges exhibiting a higher presence of chemosynthetic organisms, likely influenced by environmental factors like light and temperature.
Neuron morphology and function are highly dependent on proper organization of the cytoskeleton. In neurons, the centrosome is inactivated early in development, and acentrosomal microtubules are generated by mechanisms that are poorly understood. Here, we show that neuronal migration, development, and polarization depend on the multi-subunit protein HAUS/augmin complex, previously described to be required for mitotic spindle assembly in dividing cells.
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