Publications by authors named "I C Allen"
Based on historic observations that children with reading disabilities were disproportionately both male and non-right-handed, and that early life insults of the left hemisphere were more frequent in boys and non-right-handed children, it was proposed that early focal neuronal injury disrupts typical patterns of motor hand and language dominance and in the process produces developmental dyslexia. To date, these theories remain controversial. We revisited these earliest theories in a contemporary manner, investigating demographics associated with reading disability, and in a subgroup with and without reading disability, compared structural imaging as well as patterns of activity during tasks of verb generation and non-word repetition using magnetoencephalography source imaging.
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- SARS-CoV-2, the virus responsible for COVID-19, has led to a global pandemic with high death rates, prompting the need for more effective antiviral treatments.
- The study highlights lonafarnib (LNF), an FDA-approved drug, as an effective inhibitor against SARS-CoV-2, working well both alone and in combination with existing antivirals, while also showing effectiveness against various virus variants.
- In tests on humanized mice, LNF demonstrated the ability to reduce viral levels and improve lung health, suggesting it could be a valuable oral treatment option for COVID-19 and possibly other viral infections.
Introduction: Collaborative dementia care models with care navigation, including the Care Ecosystem, improve outcomes for persons living with dementia (PLWDs) and their caregivers. The effects of continuous care over long periods have not been studied.
Methods: In this randomized clinical trial with 456 PLWD-caregiver dyads with high caregiver burden, we evaluated the cumulative 5-year treatment effect on PLWD quality of life, health care utilization, caregiver depression, self-efficacy, and burden.
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- The article discusses community-based participatory research as a way to identify barriers preventing racially minoritized groups, particularly Black adults, from accessing cochlear implants.
- It highlights how Black adults in the U.S. face specific challenges regarding cochlear implantation and emphasizes the importance of community engagement in studying these issues.
- The Memphis SOUND Project aims to investigate hearing health disparities and has begun to share insights on both the motivating factors and obstacles Black adults face in utilizing cochlear implants.
Cross-linguistic studies with healthy individuals are vital, as they can reveal typologically common and different patterns while providing tailored benchmarks for patient studies. Nevertheless, cross-linguistic differences in narrative speech production, particularly among speakers of languages belonging to distinct language families, have been inadequately investigated. Using a picture description task, we analyze cross-linguistic variations in connected speech production across three linguistically diverse groups of cognitively normal participants-English, Chinese (Mandarin and Cantonese), and Italian speakers.
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