Background: Silver diamine fluoride (SDF) is employed in caries prevention and treatment; however, tooth discoloration post treatment is a significant disadvantage, which can be reduced using glutathione (GSH), a water soluble tripeptide.
Aim: To evaluate and compare the effect of glutathione biomolecule (GSH) and potassium iodide (KI) along with SDF on tooth discoloration and shear bond strength of glass ionomer cement (GIC) on the tooth surface.
Methods: Artificial caries were created on 48 extracted unblemished premolars and divided into four groups (SDF, SDF + KI, SDF + GSH, and Water).