Publications by authors named "I Bravo Rey"

Article Synopsis
  • Protamines are proteins vital for sperm chromatin condensation, with their expression ratios linked to fertility in different species.
  • The study aimed to evaluate RNA quality and protamine gene expression in testis samples from wild-derived mice, preserved under various conditions over different time frames.
  • Results indicated that samples preserved in RNAlater® or NAP buffer at -80°C maintained RNA integrity and protamine expression effectively, even under less optimal conditions like room temperature for a week.
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Article Synopsis
  • Sentinel lymph node (SLN) mapping in epithelial ovarian cancer may lower risks from lymphadenectomy while still providing reliable diagnostic results; ongoing research aims to evaluate its effectiveness.
  • A systematic review of four studies involving 239 patients found SLN detection rates of 59.5% for pelvic and 64.4% for para-aortic regions, with technetium-99 showing better detection rates compared to indocyanine green.
  • Diagnostic accuracy for identifying lymph node metastasis was high, reaching 100% in the pelvic field and 98.1% for the para-aortic field, suggesting SLN mapping could be a valuable tool in this context.
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: Hepatocellular carcinoma (HCC) is a leading global cause of cancer-related deaths. Thermal ablation techniques, especially radiofrequency ablation (RFA) and microwave ablation (MWA), have become pivotal treatments for HCC. This systematic review and meta-analysis aim to compare these modalities, highlighting their efficacy, strengths, and limitations in treating HCC.

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Background: The molecule known as Interleukin-8 (IL-8), a chemotactic leukocyte, has been found to have a crucial role in the perpetuation of the inflammatory environment that is associated with hepatitis B virus (HBV) infection, as well as in the development of liver cirrhosis and cancer.

Objective: The aim of this study was to carefully examine the role of IL-8 in the inflammatory reaction and to compare the levels based on the severity of liver cirrhosis.

Methods: The study was conducted from February 2018 to September 2018 at the Gastroenterohepatology Division, Internal medicine Department, Faculty of Medicine, Universitas Sumatera Utara.

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