Publications by authors named "I Bossert"
Objectives: We aimed to evaluate the clinical response to cholestyramine in patients with functional chronic diarrhea and a high clinical suspicion of bile-acid diarrhea (BAD) investigated with 75-selenium homocholic acid taurine (SeHCAT) test.
Methods: Adult patients attending our outpatient clinic between January and December 2021 for chronic diarrhea with suspicion of BAD were proposed SeHCAT testing and a therapeutic trial of cholestyramine 4-8 g daily. Clinical response to cholestyramine was evaluated at 1, 3, 6, and 12 months.
Objective: To apply a machine learning analysis to clinical and presynaptic dopaminergic imaging data of patients with rapid eye movement (REM) sleep behavior disorder (RBD) to predict the development of Parkinson disease (PD) and dementia with Lewy bodies (DLB).
Methods: In this multicenter study of the International RBD study group, 173 patients (mean age 70.5 ± 6.
Article Synopsis
- In 2005, Italy launched a voluntary iodine prophylaxis program to improve iodine levels, but recent data on its efficacy was lacking.
- A nationwide survey conducted from 2015 to 2019 observed that 71.5% of adults and 78% of school canteens used iodized salt, with schoolchildren showing adequate urinary iodine but higher rates of neonatal TSH levels than recommended by the WHO.
- Despite achieving overall iodine sufficiency, concerns about iodine status for pregnant women persist, alongside a noted decrease in new hyperthyroidism cases.
Purpose: The conventional imaging flowchart for prostate cancer (PCa) staging may fail in correctly detecting lymph node metastases (LNM). Pelvic lymph node dissection (PLND) represents the only reliable method, although invasive. A new amino acid PET compound, [F]-fluciclovine, was recently authorized in suspected PCa recurrence but not yet included in the standard staging work-up of primary PCa.
View Article and Find Full Text PDFObjective: To determine changes in clinical features and striatal dopamine reuptake transporter (DAT) density after shunt surgery in patients with idiopathic normal pressure hydrocephalus (iNPH).
Methods: Participants with probable iNPH were assessed at baseline by means of clinical rating scales, brain MRI, and SPECT with [I]-N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane (FP-CIT). Levodopa responsiveness was also evaluated.