Publications by authors named "I Bolstad"
Introduction: Smoking is negatively related to mental health, but there is a paucity of research on the relationship between the use of smokeless tobacco, such as snus, and mental health outcomes, especially in people with alcohol use disorders (AUD). The aim of the present study was to examine the development of mental distress and quality of life (QoL) among AUD patients in treatment who did or did not use snus.
Method: The study included 128 AUD patients (27% female) from three rehabilitation clinics in Eastern Norway who were interviewed at admission, at 6 weeks, and after 6 months.
Background: Comorbid anxiety and depression are common and can make the problems more complex and sometimes resistant to pharmacological treatment. In existing research, the diagnoses are often studied separately, and physical activity, healthy nutrition, psychoeducation, and social support have shown good effects. The aim of the present study was to explore the longitudinal effects of a comprehensive treatment on patients with comorbid anxiety and depression in a clinical context.
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- - FtsH, a type of protease, forms a large complex with HflK/C subunits that spans the inner membrane and interacts with the periplasm, but the process of recruiting and degrading membrane-embedded proteins is not fully understood.
- - Recent cryo-EM studies showed that when FtsH components are overproduced, the HflK/C subunits create symmetric cages that may prevent degradation of these substrates, but native complexes reveal a different structure.
- - The new asymmetrical "nautilus-like" assembly of HflK/C allows membrane-embedded substrates easier access to FtsH, which indicates that HflK/C actually facilitates the degradation process, with the complex's unique membrane curvature possibly
Aims: Patients who have undergone some forms of bariatric surgery have increased risk of developing alcohol use disorder (AUD). In the present observational study, we compared patients with AUD who themselves reported to having undergone bariatric surgery with other patients in treatment for AUD.
Materials: One-hundred-and-six consecutively enrolled patients in residential treatment for AUD were asked if they had undergone bariatric surgery.