[THE BIOMARKERS OF MYOCARDIAL DAMAGE AND THEIR ROLE IN THE PROGRESSION OF HEART FAILURE (REVIEW)].

Despite the success achieved in the study and treatment of chronic heart failure, this syndrome still remains one of the most difficult and predictable unreliable pathologies. Moreover, in recent years there has been a tendency of growth of such patients. Based on the above, the attention of scientists focuses on new concepts that involve the study of new biomarkers of cardiac damage and the definition of their role in the progression of heart failure.

Investigation of pro- and antioxidative systems' changes in blood of patients with prostate tumours.

Great number of pathogenic processes, including cancer, are followed by disbalance between pro- and antioxidative systems. This is reflected on lipid peroxidation (LP). As a result diene conjugates - the primary products of peroxidation, cetodienes, trienes (secondary products), malondialdehyde (MDA) and Schiff's bases (the final products) are synthesized.

[Proton magnetic resonance study of the changes in blood lipids in malignant and benign neoplasms].

High-resolution 1H-NMR spectrometry (360 MHz) was used in combination with thin layer chromatography to study changes in composition and molecular structure of inverted micelles of blood lipids from patients with breast and uterus cancer. Changes in relative intensity of NMR signals of lipids compared with norm were revealed. The changes in the lipid composition of blood components, in particular, in cholesterol content, determine the differences in structure and molecular mobility of these lipids, which probably explains the regularities observed in the NMR spectra.