Publications by authors named "I Bernardo"
Systemic sclerosis (SSc) is a complex connective tissue disease involving microvasculopathy, immune dysregulation, and extensive organ fibrosis. It affects various systems including the skin, lungs, heart, and gastrointestinal tract. Management is challenging due to the disease's heterogeneity and often requires more than just pharmacological treatment.
View Article and Find Full Text PDFIntroduction: The growing competitiveness and the importance of data availability for organizations have created a demand for intelligent information systems capable of analyzing data to support strategy and decision-making. Organizations are generating more and more data due to new technologies associated with Industry 4.0 and Logistics 4.
View Article and Find Full Text PDFImportance: A multicenter randomized clinical trial (RCT) showed a lung recruitment maneuver using high-frequency oscillatory ventilation just before surfactant administration (ie, intubate-recruit-surfactant-extubate [IN-REC-SUR-E]) improved the efficacy of treatment compared with the standard intubate-surfactant-extubate (IN-SUR-E) technique without increasing the risk of adverse neonatal outcomes.
Objective: To examine follow-up outcomes at corrected postnatal age (cPNA) 2 years of preterm infants previously enrolled in an RCT and treated with IN-REC-SUR-E or IN-SUR-E in 35 tertiary neonatal intensive care units.
Design, Setting, And Participants: This was a follow-up study of infants recruited into the primary RCT from 2015 to 2018 at 35 tertiary neonatal intensive care units (NICUs) in Italy.
Article Synopsis
- This study investigates the effectiveness of two surfactant administration methods—INtubate-RECruit-SURfactant-Extubate (IN-REC-SUR-E) and less invasive surfactant administration (LISA)—on improving BPD-free survival in preterm infants with respiratory distress syndrome (RDS).
- A total of 382 preterm infants, born at 24-27 weeks' gestation and not intubated at birth, will be randomly assigned to either method within the first 24 hours of life. The primary outcome being measured is a combination of death or bronchopulmonary dysplasia (BPD) at 36 weeks' postmenstrual age.
Article Synopsis
- The Quantum Anomalous Hall (QAH) insulators enable resistance-free charge transport via special edge states, but current systems face limitations with topological protection, especially at higher temperatures.
- A study using a scanning tunneling microscope reveals that the exchange gap in the QAH insulator 5-layer MnBiTe varies significantly, with fluctuations linked to magnetic disorder rather than surface defects, compromising the stability of these edge states.
- Applying a small magnetic field can restore the exchange gap in regions affected by disorder, highlighting the importance of managing magnetic disorder to utilize the unique properties of QAH insulators effectively.