Nanoparticles formed from PNIPAM-g-PEO copolymers in the presence of indomethacin.

Biocompatible double-hydrophilic PNIPAM-g-PEO copolymers containing 0.3-3.2 mol% PEO grafts were synthesized and utilized to prepare indomethacin (IMC)-loaded core-shell nanoparticles by dialysis and nanoprecipitation methods.