Initial plasma disappearance and distribution volume of [131I]albumin and [125I]fibrinogen in man.

The simultaneous plasma disappearance curves of albumin and fibrinogen were recorded in eight normal subjects from 10 to 60 min following intravenous injection. Additional samples were taken at 3, 4, 5, 6 and 7 min. The initial distribution volume (IDV) of albumin calculated by semilogarithmic extrapolation to zero time was 5.