Publications by authors named "I Bautmans"

Article Synopsis
  • Blood pressure variability (BPV) may predict negative health outcomes (NHOs) in adults aged ≥65, but current standards for what constitutes high BPV are lacking.
  • * A systematic review of 49 studies found that high systolic BPV is associated with greater odds of cardiovascular disease and cerebral deterioration compared to mean blood pressure (mBP).
  • * The study suggests that high BPV and mean BP both have significant impacts on health, with BPV offering notable predictive value, and provides guidelines for identifying elevated BPV in clinical settings.
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Article Synopsis
  • The study aimed to explore how the intensity of offset analgesia relates to pain features like conditioned pain modulation (CPM), temporal summation of second pain (TSP), and overall pain severity in people with knee osteoarthritis (KOA).
  • Researchers used electrical stimuli on 88 participants to measure these pain responses and analyzed the data using various statistical methods, excluding those who couldn't complete the tests.
  • Findings indicated that while significant pain modulation occurred, offset analgesia did not meaningfully correlate with CPM, TSP, or clinical pain severity, suggesting it may reflect other aspects of pain modulation in KOA, but its practical application is still unclear.
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: To investigate if intra-articular biomarkers relate to peripheral and central sensitization in patients with late-stage knee osteoarthritis (KOA). : A total of 17 (6M, 11F) patients (aged 69 ± 10 years) were assessed for peripheral (pressure pain thresholds (PPT)) and central (temporal summation (TS) and conditioned pain modulation (CPM)) sensitization the day before total knee arthroplasty. Synovial fluid was collected during surgery and assayed for IL-6, IL-8, IL-10, TNF-α, CXCL-10, BDNF, NGF, CCL2, CCL5, VEGF, IL-1RI, MMP-1, MMP-7, IL-1β, and CXCL-9.

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Recently, we showed that three months of resistance exercise significantly alters 18 canonical pathways related to chronic inflammation in PBMCs of older adults. In this exploratory sub-study, the aim is to explore whether resistance exercise enhances the PBMCs stress response by mimicking an acute infection through in vitro LPS stimulation. Women (≥65 years) were randomly divided into intensive strength training (IST), strength endurance training (SET), or flexibility training (as control group, CON) groups.

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Background: Monitoring the recovery trajectory during and after hospitalization can be a valuable method to observe whether additional care is needed to optimize recovery. Hand grip strength tests are commonly used to measure an individual's physical condition. Eforto® is a system to monitor hand grip strength and grip work as measures of recovery.

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