Publications by authors named "I Banu"
Article Synopsis
- The MUSIC trial tested nirsevimab, a monoclonal antibody designed to treat severe RSV infections in immunocompromised children under 24 months, assessing its safety and how the body processes the drug over time.
- Out of the 100 participants with various immunocompromising conditions, most experienced minimal side effects, with three deaths occurring that were unrelated to the treatment.
- Findings showed that nirsevimab was generally well tolerated, with serum levels indicating potential effectiveness in preventing RSV infections similar to those in healthy infants, though some children had increased drug clearance that may affect efficacy.
Pepsin, trypsin and proteinase K were used in the present study to hydrolyse the proteins from whole eggs, yolks or whites, and the resulting hydrolysates were characterised in terms of antioxidant and IgE-binding properties, using a combination of in vitro and in silico methods. Based on the degree of hydrolysis (DH) results, the egg yolk proteins are better substrates for all the tested enzymes (DH of 6.2-20.
View Article and Find Full Text PDFArticle Synopsis
- A study on children with congenital heart disease or chronic lung disease found that 200 mg nirsevimab is as safe as palivizumab for RSV prevention.
- Nirsevimab showed effective serum levels that could help protect healthy infants from severe RSV disease.
- The results suggest that nirsevimab could also be effective for children at high risk of severe RSV during their second RSV season.
Background: Fast acting insulin analogues are known to improve arterial stiffness. The combination of metformin with insulin represents a widely used therapeutic strategy in diabetes. We hypothesized that insulin treatment in patients with type 2 diabetes (T2D) with long-acting, fast-acting or basal bolus insulin as an add-on to metformin would provide additional improvement of arterial stiffness.
View Article and Find Full Text PDFSeven commercial gluten-free (rice, oat, sorghum, foxtail millet, amaranth, quinoa, and buckwheat) flours were investigated in this study from the point of view of thermo-mechanical properties and solvent retention capacity (SRC). Each flour was used to prepare doughs with specific water absorption (WA) to get a consistency of 1.1 Nm (WA1) and doughs with WA2 levels higher than 85% to ensure a sufficient amount of water in the system for allowing the hydration of all components of the flours.
View Article and Find Full Text PDF