[Chemotherapeutic effectiveness of gentamycin, tobramycin and sisomycin in Pseudomonas aeruginosa pyelonephritis in rats compared with dioxidine].

The chemotherapeutic efficacy of gentamicin, tobramycin, sisomicin and dioxydin was studied and compared in rats with hematogenic obturation P. aeruginosa pyelonephritis. The drugs were injected intramuscularly in doses of 5, 8, 8 and 50 mg/kg, respectively for 7 days a day after infection.

Influence of products of the vital activity of helminths on the corticosterone content in the adrenals and blood.

The content of corticosterone in the adrenals and blood plasma, as well as the weight of the adrenals and their histology, were investigated in 77 inbred rats (38 animals of the August line and 39 animals of the Wistar line). It was shown that after products of ascarid metabolism were administered to the experimental rats, the corticosterone content in the adrenals and blood plasma changed substantially. Despite the equal doses of the agent administered, statistically significant differences between lines were detected in the corticosterone indices in the blood plasma of the experimental rats, and they were also present in the control (healthy) animals.

[Method of morphometric study of the kidneys].

The authors describe two measuring and counting method suitable for the morphometric and histometric analysis of the main structures of the kidneys: the volume of the cortical substance and medulla, the pelvis and vessels; the quantity, the size and the volume of glomeruli.