Publications by authors named "I B Tsvetkova"

Carbapenem-resistant (CRE) are a global health threat due to their high morbidity and mortality rates and limited treatment options. This study examines the plasmid-mediated transmission of virulence and antibiotic resistance determinants in carbapenem-resistant () and () isolated from Russian hospitals. : We performed short- and long-read whole-genome sequencing of 53 clinical isolates (48 and 5 ) attributed to 15 genetic lineages and collected from 21 hospitals across nine Russian cities between 2016 and 2022.

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  • Variance in optical mesoscopic probes limits applications, especially as smaller probes show greater relative variance.
  • Specific viral protein cages, like the murine polyoma virus, can assemble efficiently and accurately, minimizing statistical fluctuations due to quality control.
  • An approach leveraging this assembly results in multichromophore particles that produce brighter, more consistent fluorescence than existing fluorescent nanosphere probes, validated by mass spectrometry and fluorescence microscopy.
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  • Natural deep eutectic solvents (NADESs) are being explored as eco-friendly alternatives to traditional solvents for extracting beneficial compounds from natural sources, specifically focusing on phenolic compounds from poplar propolis.
  • The study evaluated five different NADESs for their effectiveness in extracting these compounds, finding that their chemical profiles were similar to those of extracts made with 70% ethanol.
  • Results indicated that using NADESs not only yielded good amounts of phenolic compounds but also preserved or enhanced the biological activity of the extracts, with low toxicity and variable genotoxicity compared to conventional methods.
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  • * A study analyzed 696 URT samples from 285 COVID-19 patients and 100 healthy controls, revealing significant differences in microbial composition, with COVID-19 patients showing reduced abundance of 16 bacterial genera and unique taxa not found in healthy individuals.
  • * As COVID-19 patients underwent treatment, certain depleted bacteria (like Fusobacterium and Neisseria) increased, suggesting recovery as their URT microbiome composition began resembling that of healthy individuals, indicating a shift towards stability.
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() is a ubiquitous microorganism with pathogenic and saprophytic clones. The objective of this study was to evaluate the presence, virulence, antibiotic resistance and biofilm formation of in three industrial farms in Bulgaria, as well as their adjacent sites related to the utilization of manure (feces, wastewater in a separator, lagoons, means of transport, and soils). The isolation of single bacterial cultures was performed via standard procedures with modifications, and isolates were identified via matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and polymerase chain reaction (PCR).

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