Insights Into the Mechanisms of Tonoplast Dicarboxylate Transporter-Induced Plant Tolerance Against Manganese Toxicity in Peach.

Manganese (Mn) toxicity poses a severe hazard to plant growth, with organic acids playing a crucial role in detoxifying toxic metals. However, the regulatory mechanisms governing the response of organic acids to Mn toxicity remain largely elusive, particularly in perennial fruit crops. Herein, we investigated the physio-biochemical and transcriptomic responses of peach seedlings to Mn toxicity.

Inhibition of Shiga Toxin 2 for E. coli O157 Control: An In-Silico Study on Natural and Synthetic Compounds.

Introduction/objectives: Escherichia coli strains are known to cause various gastrointestinal disorders, with Shiga toxin 2, a potent cytotoxin, being a key virulence factor contributing to disease severity. Targeting Shiga toxin 2 presents a promising approach for therapeutic intervention in controlling E. coli O157 infections.