Publications by authors named "I B Johansen"
Background And Aims: The emergence of biologic therapy has coincided with a decline in surgery rates for Crohn's disease (CD). This study aims to describe the disease course, including intra-abdominal surgery rates, biologic therapy use, and variables associated with biologic therapy initiation in a cohort of newly diagnosed CD patients.
Methods: The Inflammatory Bowel Disease in South-Eastern Norway (IBSEN) III study is a population-based inception cohort study.
The potato family includes a highly diverse cultivar repertoire and has a high potential for nutritional yield improvement and refinement but must in line with other crops be adapted to biotic and abiotic stresses, for example, accelerated by climate change and environmental demands. The combination of pluripotency, high ploidy, and relative ease of protoplast isolation, transformation, and regeneration together with clonal propagation through tubers makes potato highly suitable for precise genetic engineering. Most potato varieties are tetraploid having a very high prevalence of length polymorphisms and small nucleotide polymorphisms between alleles, often complicating CRISPR-Cas editing designs and strategies.
View Article and Find Full Text PDFObjective: To investigate the use of non-barrier contraceptives among women with HIV (WWH) compared to women from the general population (WGP) in Denmark.
Design: Nationwide population-based matched cohort study.
Methods: We included WWH aged 16-50, treated at an HIV specialized clinic, and included in The Danish HIV Cohort Study between 1995-2021 and an age-matched comparison cohort of WGP.
Article Synopsis
- The study examined the relationship between bipolar disorders and the risk of HIV infection, as well as the risk of bipolar disorders in people with HIV (PWH) and their siblings.
- It used data from a large Danish population-based study, analyzing information from over 5,000 PWH and more than 53,000 matched individuals from the general population.
- Results showed that bipolar disorder increases the risk of HIV infection significantly, especially among injection drug users, and that PWH have a notably higher risk of developing bipolar disorder, particularly in the first two years after diagnosis.
Article Synopsis
- Recent guidelines for women living with HIV in high-income countries emphasize shared decision-making, yet there's limited understanding of their infant feeding knowledge and healthcare provider interactions.
- This study, conducted in Denmark, Finland, and Sweden, involved pregnant women living with HIV, gathering both quantitative data through a survey and qualitative insights from interviews to explore their knowledge and experiences over time.
- Results revealed that women were confused about breastfeeding in relation to the U=U concept, with Nordic women showing more uncertainty than those from non-Nordic backgrounds, while ongoing monitoring of mothers was not perceived as a barrier to breastfeeding.