Publications by authors named "I B Giorgobiani"

Using high-performance liquid chromatography were qualitatively and quantitatively identified high fatty acids contained in grape seed oil and compare its biological activity as 1,0% and 2,5% food-additive an fatty acids composition contained in lipids of mice livers. Investigation were carried out on 90 inbred mice 5,0 g weight. Using high-performance liquid chromatography methods in grape seed oil is identified linoleic (65,0%), linolenic (1,5%), oleic (17,0%), palmitic (8,0%), stearic (4,4%) and arachidonic (0,6%) acids.

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The aim of the study is individual identification of fatty acids in oil of Chelidonium majus L. and prediction of its effects as a food-additive. By high-effective liquid chromatographic methods, fatty acids were fractionated.

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In this paper, using high-performance liquid chromatography methods were quantitatively and qualitatively identified most biological important high fatty acids, contained in Rkatsiteli grape seed oil of 2010 years crop in Signakhi region of Georgia. The chromatography investigation showed, that the grape seed oil contained 61% linolic acid, 19% oleic, 8% palmitic, 4.5% stearic, 1.

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In this paper high fatty acids in the Rkatsiteli grape seed oil were qualitatively and quantitatively identified. In the Rkatsiteli grape seed oil linolenic, oleic, palmitic, stearic, palmitooleinovaya, linoleic and arachidonic acids were identified. The impact of Rkatsiteli grape seed oil as a dietary supplement on the contents of fatty acid synthase and lipids in the livers of mice were determined.

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Antidepressant Fluoxetine and their major therapeutically active metabolite Norfluoxetine was monitored in albumene and glicoproteene of blood plasma and washed from eritrozite supernatant. In paper we describe rapid and reliable method using high-performance liquid chromatography for simultaneous measurement of plasma and supernatant concentration of Fluoxetine and Norfluoxetine. The described method has been successfully used in clinical and laboratory cases.

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