Publications by authors named "I B"
Coronavirus disease 2019 is a global pandemic, and to deal with the unexpected, enormous burden on healthcare system, liver transplantation (LT) services have been suspended in many centers. Development of robust and successful protocols in preventing the disease among the recipients, donors and healthcare workers would help in re-starting the LT programs. We adapted a protocol at our center, which is predominantly a living donor liver transplant center based in north India, and continued the service as the pandemic unfolded and peaked in India with good results and shared the experience of the same.
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- Strain JC507 is a Gram-stain-negative, rod-shaped, and non-motile bacterium isolated from yeast, showing positive oxidase and catalase reactions.
- Genetic analysis showed it closely relates to NBRC 14944 (98.7% similarity), indicating it belongs to a new species within its genus.
- Its unique fatty acid profile and distinct genomic characteristics propose the name “sp. nov.” for this new species, with JC507 identified as the type strain.
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- All three domains of life rely on a structured plasma membrane for survival, with hopanoids playing a crucial role in bacterial membrane stability similar to cholesterol in eukaryotes.
- A study on the genome-wide transcriptome of Rhodopseudomonas palustris showed that hopanoid deficiency upregulated 299 genes and downregulated 306 genes, affecting functions such as chemotaxis and membrane transport.
- Disruption of hopanoid synthesis could lead to new antimicrobial strategies, particularly by targeting lipid synthesis to compromise membrane integrity.
This study was conducted to characterize canine bone marrow-derived mesenchymal stem cells (BMSCs); in vivo tracking in mice, and therapeutic evaluation in canine clinical paraplegia cases. Canine BMSCs were isolated, cultured, and characterized in vitro as per International Society for Cellular Therapy criteria, and successfully differentiated to chondrogenic, osteogenic, and adipogenic lineages. To demonstrate the homing property, the pGL4.
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- Thermal stress is a significant issue affecting dairy cattle productivity in India, particularly for high-producing cows, which necessitates effective strategies to reduce heat and calving-related stress for better economic outcomes.
- The study investigated the effects of inorganic zinc supplementation on thermal stress in periparturient cows, specifically focusing on two breeds: Sahiwal and Karan Fries, by analyzing blood samples and the response of isolated peripheral blood mononuclear cells (PBMC) under controlled thermal conditions.
- Results indicated that while thermal stress led to increased levels of heat shock proteins (HSP) and Interleukin 6 (IL-6), zinc treatment effectively reduced these stress markers and improved immunity in the cows, suggesting that mineral supplementation could enhance resilience to heat