The Therapist as a Collaborative Pianist.

In this article we seek to examine what we might learn about the therapist/psychoanalyst's function as selfobject by examining the relationship between the "vocal persona" and the "instrumental persona" in the art song. The comparison was born out of our own life partnership as a therapist, currently studying in a psychoanalytic-Buddhist training program that stresses the presence of the therapist/psychoanalyst as selfobject; and a collaborative pianist who instructs and performs with singers onstage. The concept of selfobject has offered a compelling and fruitful analogy.

The Pursuit of COVID-19 Biomarkers: Putting the Spotlight on and Regulatory Sequences.

Diverse populations worldwide are differentially affected by coronavirus disease 2019 (COVID-19). While socioeconomic background has been studied extensively, little is known about the genetic variation underlying this phenomenon. This study is aimed at examining the genetic basis behind the great discrepancies among diverse ethnic groups in terms of COVID-19 susceptibility for viral infection, disease prognosis, and mortality.

Trophoblast lineage specific expression of the alternative splicing factor RBFOX2 suggests a role in placental development.

Introduction: RBFOX2, an RNA-binding protein, controls tissue-specific alternative splicing of exons in diverse processes of development. The progenitor cytotrophoblast of the human placenta differentiates into either the syncytiotrophoblast, formed via cell fusion, or the invasive extravillous trophoblast lineage. The placenta affords a singular system where a role for RBFOX2 in both cell invasion and cell fusion may be studied.

Aberrant corin and PCSK6 in placentas of the maternal hyperinsulinemia IUGR rat model.

Objectives: Corin is a protease that converts pro-atrial natriuretic peptide (pro-ANP) to ANP. While the involvement of ANP in the cardiovascular regulation is well established, there is increasing evidence that the pregnant uterus produces ANP, which promotes spiral artery remodeling. The present study examines the alterations in corin and PCSK6, a key enzyme in the conversion of pro-corin to corin, in the placenta of hyperinsulinemic dams (HD) featuring pregnancy-induced hypertension (PIH).