Publications by authors named "I Antonyan"
Background: The standard of care for locoregional renal cell carcinoma is surgery, but many patients experience recurrence. The objective of the current study was to determine if adjuvant atezolizumab (vs placebo) delayed recurrence in patients with an increased risk of recurrence after resection.
Methods: IMmotion010 is a randomised, double-blind, multicentre, phase 3 trial conducted in 215 centres in 28 countries.
The study included 12 patients who underwent extracorporeal nephron-sparing surgery followed by autotransplantation of the kidney to the iliac region. A solitary kidney occurred in 7 (58.3%) cases, bilateral tumors in 2 (16.
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- - The paper examines the long-term outcomes of ureterocalicostomy (UC) in 37 patients, with a majority undergoing secondary procedures for conditions like hydronephrosis or kidney stones.
- - Surgical resections were categorized by the thickness of kidney tissue removed, revealing that most had significant lower pole removals, and complications were mostly mild (Grade I-II) occurring in 37.8% of cases.
- - Overall, 81.1% of patients achieved good results post-surgery, with the thickness of renal parenchyma under 10 mm identified as a key predictor for poorer outcomes.
In most cases RCC with venous extension is an indication for radical nephrectomy. However, in patients with imperative indications for nephron-sparing surgery a kidney resection with thrombectomy in rare situations is possible. We present a surgical technique for nephron-sparing surgery in patients with tumor spreading into the main renal vein.
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