Clinical study of the effect of the preparation DEODAN on leukopenia, induced by cytostatics.

The aim of the study is to establish the effect of the preparation DEODAN on leukopenia induced by chemotherapeutics in oncological patients. DEODAN is an oral preparation, obtained from lyzozyme lysates of Lactobacillus bulgaricus strain "I. Bogdanov patent strain tumoronecroticance B-51" ATCC 21815, called shortly LB51.

Changes in interdigestive migrating electric complex induced by motion sickness.

This study aimed to investigate, by means of an intralumenal recording technique, the influence of motion sickness on the interdigestive migrating electric complex (IDMEC) of the gastrointestinal system of susceptible subjects. The results indicate that vestibular stimulations significantly change the duration of IDMEC phases (p < 0.05 and p < 0.

Changes in the gastrointestinal electric pattern to motion sickness in susceptibles and insusceptibles during fasting.

The cardinal symptoms of motion sickness occur in the gastrointestinal system. This study sought to investigate the influence of sickness-provoking motion stimuli on the interdigestive migrating electric complex (IDMEC) of the gastro-intestinal system. Thirteen susceptibles and 14 insusceptibles to motion sickness were subjected to intralumenal recording before and after caloric vestibular stimulations.

Modulation of the adrenergic system in the treatment of postoperative bowel atonia.

Sympathetic hyperactivity is considered to be the most important factor in the development of postoperative bowel atonia. In a double-blind study we evaluated the gut motor effects of dihydroergotamine, which predominantly acts as a sympatholytic agent in the gastrointestinal tract. Forty-six patients undergoing cholecystectomy received either 0.

Local inhibition of myoelectrical activity of human colon by loperamide.

In order to study whether the antidiarrheal effects of loperamide are largely brought about by a local inhibition of the drug, we applied doses of 0.2 mg directly on the mucosa of the descending and sigmoid colon of 33 healthy volunteers. Loperamide decreased BER frequencies and reduced spike activity to 6.