Publications by authors named "I Al-Hadabi"
Article Synopsis
- The study examined how clinical and demographic factors affect the effectiveness of Whole Exome Sequencing (WES) for diagnosing Autism Spectrum Disorder (ASD) in children from a consanguineous background.
- Out of 97 children analyzed, 63% were male, with a high percentage (77.3%) suspected of having a syndromic cause; many also had additional health conditions including central nervous system issues.
- The overall diagnostic success of WES in identifying genetic causes for ASD was 34%, with children experiencing seizures having higher positive results (46% vs. 31%).
Aim: To describe the clinical and histopathological features of ocular reactive lymphoid hyperplasia in children, and review the literature regarding this entity.
Materials And Methods: In this retrospective, interventional case series, a chart review was performed of three patients diagnosed with reactive lymphoid hyperplasia. Details of clinical presentation, ocular and systemic examination findings, management and subsequent course were noted.
Gastric cancer remains a significant global health burden with poor treatment outcome. New treatment modalities that target inflammation, proliferation, and angiogenesis have been used in various cancers, including gastric cancer. We sought to study the pattern of expression of two important proteins, cyclooxygenase-2 and epidermal growth factor receptor, and their association with microvascular density, clinicopathological features, and survival in Arab Omani patients with gastric cancer.
View Article and Find Full Text PDFBackground: The variability of prognosis within a pathological stage of gastric cancer (GC) at presentation, underscores the need for specific biological markers to identify subgroups of patients with aggressive course for intensive treatment. To our knowledge, this is the first study from an Arab population reporting on the relationship of p53, p27 kip1, p21 waf1, HER-2/neu, and Ki67 expression, and clinicopathological features and their prognostic significance.
Methods: Formalin-fixed paraffin-embedded tumors were studied by immunohistochemistry, using monoclonal antibodies to p53, p27 kip1, p21 waf1, HER-2/neu, and Ki67.