Slit and Robo control the development of dendrites in Drosophila CNS.

The molecular mechanisms that generate dendrites in the CNS are poorly understood. The diffusible signal molecule Slit and the neuronally expressed receptor Robo mediate growth cone collapse in vivo. However, in cultured neurons, these molecules promote dendritic development.

Gliopodia extend the range of direct glia-neuron communication during the CNS development in Drosophila.

Midline glia are a source of cues for neuronal navigation and differentiation in the Drosophila CNS. Despite their importance, how glia and neurons communicate during the development is not fully understood. Here, we examined dynamic morphology of midline glia and assessed their direct cellular interactions with neurons within the embryonic CNS.

Stress-reactivity of a Drosophila melanogaster strain with impaired juvenile hormone action.

Met(27) is a null allele of the Methoprene-tolerant gene of D. melanogaster that shows resistance to the toxic effects of both juvenile hormone (JH) and a JH analog, methoprene. The mechanism of resistance appears to be altered JH reception.

[The dopamine system stress reaction in adults of Drosophila virilis is controlled by genes of Chromosome 6].

A linkage group of the gene responsible for changes of DA titer under stress in adults of D. virilis was determined. Line 160 of D.

[Some regularities in the genetic control of the stress reaction in Drosophila].

The heat-shock response was studied in Drosophila virilis strains with normal and impaired neurohormonal stress reaction. Flies from the latter strain were shown to have the impaired heat-shock response. In this strain, transcription of the heat shock gene hsp83 is reduced and synthesis of all heat shock proteins is suppressed.