Multidimensional role of selenium nanoparticles to promote growth and resilience dynamics of against sodium fluoride stress.

High fluoride (F) concentrations negatively affect the seed germination, plant growth, development, and yield of crops. L. is an F-sensitive crop frequently grown on marginal lands affected by F salts.

PREVALENCE AND DETERMINANTS OF SHISHA SMOKING AMONG GOMBE STATE UNIVERSITY STUDENTS.

Introduction: Emerging literature suggests that shisha smoke contains many of the same toxicants as cigarette smoke, including carcinogenic polycyclic aromatic hydrocarbons. A single shisha smoking session may involve inhalation of 50-100 times the smoke volume inhaled with a single cigarette. While tobacco control policies have largely centered on cigarette smoking, other forms like shisha, have largely been ignored.

Possible involvement of sialidase and sialyltransferase activities in a stage-dependent recycling of sialic acid in some organs of type 1 and type 2 diabetic rats.

Background: Type 1 (T1D) and type 2 (T2D) diabetes lead to an aberrant metabolism of sialoglycoconjugates and elevated free serum sialic acid (FSSA) level. The present study evaluated sialidase and sialyltranferase activities in serum and some organs relevant to diabetes at early and late stages of T1D and T2D.

Methods: Sialic acid level with sialidase and sialyltransferase activities were monitored in the serum, liver, pancreas, skeletal muscle and kidney of diabetic animals at early and late stages of the diseases.

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction.

Subclonal reconstruction algorithms use bulk DNA sequencing data to quantify parameters of tumor evolution, allowing an assessment of how cancers initiate, progress and respond to selective pressures. We launched the ICGC-TCGA (International Cancer Genome Consortium-The Cancer Genome Atlas) DREAM Somatic Mutation Calling Tumor Heterogeneity and Evolution Challenge to benchmark existing subclonal reconstruction algorithms. This 7-year community effort used cloud computing to benchmark 31 subclonal reconstruction algorithms on 51 simulated tumors.