Microbiological and molecular identification of the anaerobic component of the oral microbiota in patients with cancer of the oropharyngeal region.

A research objective - to study tumor tissues of primary and recurrent patients with cancer of the oropharyngeal region for the frequency of occurrence of four types of anaerobic periodontogens and their associations by two methods: real-time PCR and cultural. There is speculation that bacteria can influence the pathogenesis of cancer. A comparative assessment of the content of four anaerobic periodontogens (Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis, Treponema denticola) in the tumor tissue and in the healthy tissue of the oral mucosa of patients with oropharyngeal cancer was carried out.

The role of chromodomain helicase DNA binding protein 1 (CHD1) in promoting an invasive prostate cancer phenotype.

Background: Prostate cancer (PCa) phenotypes vary from indolent to aggressive. Molecular subtyping may be useful in predicting aggressive cancers and directing therapy. One such subtype involving deletions of chromodomain helicase DNA binding protein 1 (), a tumor suppressor gene, are found in 10-26% of PCa tumors.

Complex interactions between meteorological parameters and the thermal regime of two tropical, high altitude crater lakes (Nevado de Toluca, Mexico).

Using long-term time series of meteorological and water-column parameters, the dynamics of two lakes separated by about 500 m from each other by a central lava dome, located at 4207 m above sea level in the volcano crater of Nevado de Toluca, Mexico were explored. Because of the strong wind-forcing previously measured on the volcano slope and the proximity of the lakes, wind-mixing was expected, with similar dynamics in both lakes. However, the meteorological parameters in the crater were significantly different than on the slope of the volcano, due to the dome and the high walls of the crater, which weakened wind speeds, modified wind direction, and reduced exposure to solar radiation by almost 20% in the crater compared to on the volcano slope.

Natural Frequencies of seiches in Lake Chapala.

This research presents an analysis of the frequencies and vibration modes of the structure of the superficial seiches of Lake Chapala using mathematical modelling and measurements. The HAMSOM model was run with wind fields from coastal meteorological stations and for different lake storage levels. The lake water level measurements were carried out in two campaigns in 2003.