Publications by authors named "I A Taiwo"
Lateritic soil, a prevalent geological material in tropical regions, often exhibits poor engineering properties, leading to road pavement failures. Meanwhile, the alarming rise in plastic waste poses environmental concerns. This innovative study explores the potential of utilizing waste plastics as a lateritic soil addictive for sustainable road construction.
View Article and Find Full Text PDFA 5-year review of research ethics applications in a tertiary health and educational institution in Nigeria.
Afr Health Sci
September 2023
Background: African contribution to global research output is said to be low. Poor funding and poor skills in grant writing have been suggested as important factors for this situation.
Objectives: Applications for research ethics clearance in a hospital were reviewed to have an overview of the planned studies and the proportion of them that attracted national and international funding.
Article Synopsis
- - The study examined how the storage duration of formalin-fixed paraffin-embedded (FFPE) lymphoma biopsies from Nigeria affected the integrity and quantity of extracted nucleic acids, which are important for cancer diagnosis and treatment.
- - A total of 53 FFPE biopsies were analyzed, revealing that despite varying storage times (from 2008-2019), the means yields of DNA and RNA were consistent, with no significant differences in quality across the samples.
- - Results showed good quality DNA and RNA, indicating that even archived samples can still provide reliable genetic material for analysis, essential for effective cancer research and therapy.
Low frequency of knockdown resistance mutation (L1014F) and the efficacy of PBO synergist in multiple insecticide-resistant populations of Anopheles gambiae in Ikorodu, Lagos State, Nigeria.
Afr Health Sci
March 2023
Objective: We evaluated the susceptibility status of Anopheles gambiae in two communities of Ikorodu, Lagos, Nigeria to DDT, deltamethrin, lambda cyhalothrin and bendiocarb.
Methods: immature stages were collected from their habitats in the surveyed community and allowed to emerge before exposure adult females to discriminating doses of WHO insecticides including DDT, deltamethrin, lambda cyhalothrin, bendiocarb and malathion. PBO synergistic bioassay was conducted for insecticides where the mosquito samples showed resistance.
Background: Sickle cell disease is the commonest genetic disorder in Nigeria, affecting 2-3% of an estimated population of 160 million people. The role of genetic mutations in folate cycle genes, and the variable phenotypic expressions constituting disease severity, needs to be critically examined.
Objective: This study was carried out to establish the pattern of methionine synthase gene mutations (rs1805087 SNP), and its possible association with disease severity in adults with sickle cell anaemia in Lagos, Nigeria.