[The effect of the acute administration of ethanol on the realization of behavior and its neuronal support].

In experiments on rabbits trained to instrumental food procuring behaviour it was cleared up, which changes of activity of neurones of the limbic cortical area corresponded to disturbances of this behaviour (increase in time of realization and in the number of errors) caused by intraperitoneal injection of 12% ethanol solution in a dose of 1 g/kg. In comparison with control (administration of isotonic solution), the number of active cells singled out in the microelectrode track was reduced by 1/3; the pattern of behavioural specialization of neurones involved in provision of the disturbed behaviour was changed. The content of neurones of the most recent systems formed during animals learning instrumental behaviour, decreased from 27 to 11%, and of neurones providing for realization of systems formed at previous stages of individual development increased from 18 to 36%.

[Correlation between the in vivo dynamics of redox processes and neuronal electrical activity in response to angiotensin II and cyclic AMP].

The biologically active substances induced mostly similar changes of the restorative equivalents level whereas the pattern of equivalents varied in neuronal activity of the mammal brain cortex. The effects of angiotensin II and cAMP on neuronal activity were different. The data obtained suggest that the angiotensin II effect on neurons is actualized both through the cAMP system and through other molecular mechanisms.