[Multifocal electroretinography in assessment of the functional state of the central retina in patients with retinitis pigmentosa].

Unlabelled: Retinitis pigmentosa (RP) is an inherited disease associated with various genetic mutations. Developments in the field of genetic engineering give relevance to the search for methods of studying retinal function, which can prove informative in the selection of patients for treatment.

Purpose: To evaluate the information content of multifocal electroretinography (mfERG) in the diagnostics of the functional state of the central retina in retinitis pigmentosa (RP).

Electrophysiological and psychophysical studies in assessment of visual functions in patients with hereditary optic neuropathy.

Purpose: To study the capabilities of electrophysiological and psychophysical examination methods for assessment of the functional state of ganglion cells, retina and optic nerve in patients with hereditary optic neuropathy (HON).

Material And Methods: The study included 60 patients (118 eyes) with a genetically confirmed diagnosis of HON. All study patients underwent visual field test (VFT), spectral optical coherence tomography (OCT), flash and pattern visual evoked potentials (VEP) (Flash-VEP, FVEP; Pattern-VEP, PVEP), photopic electroretinography with photonegative response (PhNR) registration and the color vision test.

[Asymmetric form of pigmentary retinopathy (case study)].

Unilateral pigmentary retinopathy (PR) is a rare, atypical form of hereditary retinal pathology. Different types of secondary retinopathy associated with various non-hereditary diseases, trauma or intoxication can imitate unilateral PR. Therefore, it is important to determine the cause of visual disorders and differentiate between unilateral and asymmetric PR.

[Performance evaluation of multifocal electroretinography for monocular and binocular stimulation in anisochromoartiphakia].

Unlabelled: Multifocal electroretinography (mfERG) helps evaluate the electrical potential of the retina in a set of points within 30 degrees. There is a significant number of factors affecting the value of mfERG data, which should be taken into account in research studies.

Purpose: To evaluate the difference and nature of changes in the amplitude (P1) and latency (P1, L1) parameters of mfERG in monocular (MS) and binocular stimulation (BS) in individuals with anisochromoartiphakia.

[Morphological and functional indicators of retinal pigment epithelium and photoreceptor apparatus in inherited retinal diseases].

Purpose: To evaluate the relationship between the morphological and functional parameters of retinal pigment epithelium (RPE) and photoreceptors (PR) in inherited retinal diseases (IRD).

Material And Methods: The study included 52 patients (104 eyes), 23 of them with Stargardt Disease (STGD), 19 with cone-rod dystrophy (CRD), 10 with retinitis pigmentosa/pigmentary abiotrophy (RP) of comparable disease durations. All patients underwent standard and additional ophthalmological examination: fundus autofluorescence (AF), spectral optical coherence tomography (OCT), computer perimetry (CP), electro-oculography (EOG), Ganzfeld electroretinography (gERG).