Evaluation of the Neuroprotective Effect of Magnesium-Bis-(2-Aminoethanesulfonic)-Butanedioate in Simulated Ischemic Stroke in Rats.

Sudden loss of blood flow to an area of the brain causes ischemic stroke, which leads to the loss of nerve function in the brain. The brain tissue leads to the death of brain cells in less than a few minutes due to the lack of oxygen and nutrients. This study aimed to evaluate the effectiveness of pharmacological correction of the consequences of ischemic stroke with a new derivative of taurine magnesium-bis-(2-aminoethanesulfonic)-butanedioate under laboratory code LKHT 3-17 in rats.

Investigation of Taurine Derivative Magnesium-Bis-(2-Aminoethanesulfonic)-Butadioateon Alleviation of Neurological Defects in Simulated Hemorrhagic Stroke in Rats.

Stroke or ischemia is caused by a blockage in a specific blood vessel that partially or completely reduces the blood flow to the brain. Nutritional factors such as antioxidants and healthy eating patterns are important variables in preventing stroke. Molecular composition properties such as molecular binding and screening can be used to evaluate the specific activity and morphological changes.

[Anti-glomerular basement membrane glomerulonephritis concurrent with membranous nephropathy].

The paper describes a case of anti-glomerular basement membrane glomerulonephritis (anti-GBM GN) concurrent with membranous glomerulopathy (MGP) in a 25-year-old female patient. The diagnosis was established on the basis of clinical, laboratory, and pathomorphological data, including electron microscopic ones). The comprehensive analysis, including ultrastructural diagnosis, is shown to be important in identifying this rare combination of two nosological entities, anti-GBM GN and MGP, in the same patient.

[Detection of bensultap (bancol) derivatives and metabolites by chromatographic methods].

This paper is designed to describe methods for the detection of derivatives and metabolites of the insecticidic agent bancol (nereistoxin precursor) by chromatographic methods including thin layer chromatography (TLC), high-performance liquid chromatography (HPLC), gas chromatography with a nitrogen-phosphorous detector (GC-NPD), and gas chromatography mass spectrometry (GH-MS). The data obtained confirm the high diagnostic value of assays for derivatives and metabolites compared with the determination of the respective parent insecticides. New variants of extraction of these compounds from urine and various tissues by liquid-liquid and solid-phase chromatography are proposed.