Publications by authors named "I A Pak"
Urinary tract infection is a frequent problem after stroke. Although prior scoring systems for UTI after stroke have been developed, we developed a simple scoring system for all types of stroke in our own. The study was designed on retrospective data.
View Article and Find Full Text PDFEmerging evidence suggests that personalized dietary supplement regimens can significantly influence lipid metabolism and cardiovascular risk. The efficacy of AI-guided dietary supplement prescriptions, compared with standard physician-guided prescriptions, remains underexplored. In a randomized, parallel-group pilot study, 70 patients aged 40-75 years with LDL-C levels between 70 and 190 mg/dL were enrolled.
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- The study investigates the link between acute kidney injury (AKI) and outcomes in patients with spontaneous subarachnoid hemorrhage (SAH), a serious condition with a high risk of complications.
- An analysis of over 76,000 SAH patients from 2010 to 2019 shows that about 14% developed AKI, with these patients being older and more likely to be obese compared to those without AKI.
- Findings indicate that AKI is significantly associated with poorer functional outcomes, longer hospital stays, and higher in-hospital mortality, highlighting the need for early detection to improve recovery chances.
Exploring the link between genetic polymorphisms in folate metabolism genes (MTHFR, MTR, and MTRR) and cardiovascular disease (CVD), this study evaluates the effect of B vitamin supplements (methylfolate, pyridoxal-5'-phosphate, and methylcobalamin) on homocysteine and lipid levels, potentially guiding personalized CVD risk management. In a randomized, double-blind, placebo-controlled trial, 54 patients aged 40-75 with elevated homocysteine and moderate LDL-C levels were divided based on MTHFR, MTR, and MTRR genetic polymorphisms. Over six months, they received either a combination of methylfolate, P5P, and methylcobalamin, or a placebo.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus (DM) remains the most common type of DM and is associat-ed with disabling complications, reduced quality of life and reduced life expectancy. Satisfactory control of carbohydrate metabolism remains the key way to manage them.
Aim: To perform a retrospective analysis of carbohydrate metabolism (in terms of glycated hemoglobin - HbA), the prevalence of complications, and features of hypoglycemic and concomitant therapy in patients with type 2 DM.