Publications by authors named "I A Merai"
Article Synopsis
- The study aimed to compare the clinical features, treatment options, and outcomes of patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) to those with obstructive coronary arteries (MIOCA).
- Of the 712 patients analyzed, 73 were diagnosed with MINOCA, predominantly affecting younger women, with common causes being discrepancies in myocardial oxygen supply and demand, along with hypertensive crises.
- Results indicated that treatment for MINOCA patients was less aggressive than for MIOCA patients, yet their short-term and long-term mortality rates were similar, underscoring the urgent need for better management strategies for MINOCA.
Background: Despite the poor prognosis in patients with type 2 myocardial infarction (MI), no prospective data on risk stratification exists. The aim of this study was to develop and validate a model for prediction of 18-month mortality of among patients with type 2 MI (T2MI) and compare its performance with GRACE and TARRACO scores.
Methods: The prospective observational study included 712 consecutive patients diagnosed with MI undergoing coronary angiography <24 h between January 2017 and December 2018.
Concordance and Prognostic Relevance of Angiographic and Clinical Definitions of Myocardial Infarction Type.
J Cardiovasc Pharmacol Ther
September 2021
Background: Atherothrombosis is the principal mechanism of type 1 (T1) myocardial infarction (MI), while type 2 (T2) MI is typically diagnosed in the presence of triggers (anemia, arrhythmia, etc.). We aimed to evaluate the proportions of T1 vs.
View Article and Find Full Text PDFAims: Patients admitted for acute heart failure (HF) are at high risk of readmission and death, especially in the 90 days following discharge. We aimed to assess the safety and efficacy of early optimization of oral HF therapy with beta-blockers (BB), angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARB) or angiotensin receptor-neprilysin inhibitors (ARNi), and mineralocorticoid receptor antagonists (MRA) on 90-day clinical outcomes in patients admitted for acute HF.
Methods: In a multicentre, randomized, open-label, parallel-group study, a total of 900 patients will be randomized in a 1:1 ratio to either 'usual care' or 'high-intensity care'.