Effects of alpha-2-adrenoceptor agonism and antagonism on equine blood insulin and glucose concentrations after oral carbohydrate load.

Alpha-2-adrenoceptor agonist detomidine is a commonly used sedative agent in horses. In addition to the sedative effect, detomidine has been reported to elicit changes in energy metabolism such as hypoinsulinaemia and hyperglycaemia. This study aimed to investigate the effects of detomidine with and without peripherally acting alpha-2-adrenoceptor antagonist vatinoxan on insulin and blood glucose (BG) concentrations in horses after a standard dose of oral carbohydrates.

Effect of constant rate infusion of detomidine with and without vatinoxan on blood glucose and insulin concentrations in horses.

Objective: To assess the effects of an α-adrenoceptor agonist (detomidine) constant rate infusion (CRI) with and without an α-adrenoceptor antagonist (vatinoxan) CRI on blood insulin and glucose concentrations, heart rate, intestinal borborygmi, and sedation during and after infusion in horses.

Study Design: Randomized, blinded, crossover, experimental study.

Animals: A total of nine healthy, adult Finnhorse mares.

RNA hybridization of in equine endometrial biopsies.

Endometritis is one of the major causes of infertility in mares. and -haemolytic streptococci are among the bacterial species most frequently isolated from the equine uterus. Some bacteria such as -hemolytic streptococci, can persist in dormant forms and cause prolonged, latent or recurrent infections.

The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review.

Obesity is a growing welfare concern in modern equine populations and predisposes horses to disturbances in energy metabolism such as insulin dysregulation. However, equine metabolic syndrome has only been recognized in recent decades. Functioning energy metabolism is pivotal to normal body homeostasis and affects essentially all organ systems, including reproduction.

Improving the culture of safety on a high-acuity inpatient child/adolescent psychiatric unit by mindfulness-based stress reduction training of staff.

Problem: The purpose of this study was to reduce perceived levels of interprofessional staff stress and to improve patient and staff safety by implementing a brief mindfulness-based stress reduction (MBSR) training program on a highacuity psychiatric inpatient unit.

Methods: A one-group repeated measure design was utilized to measure the impact of the (MBSR) training program on staff stress and safety immediately posttraining and at 2 months. Two instruments were utilized in the study: the Toronto Mindfulness Scale and the Perceived Stress Scale.