Publications by authors named "I A Lahlou"
Ewing's sarcoma can affect any bone. Primary localization in the coracoid process is extremely rare and atypical. In the literature there have been a few reports of Ewing's sarcoma of the scapula.
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- This study analyzed genetic changes in non-small cell lung cancer (NSCLC) patients from Morocco and compared them to data from the Cancer Genome Atlas (TCGA).
- Out of 76 tissue samples analyzed, 70 had genetic alterations, with 234 changes identified across 18 genes that could influence targeted therapy decisions.
- Significant differences were found in the prevalence of certain mutations between Moroccan patients and TCGA data, reinforcing the importance of next-generation sequencing for effective diagnosis and treatment planning in NSCLC.
Botryoid rhabdomyosarcoma is a rare and aggressive malignancy that primarily affects the female genital tract in children. It arises from embryonal rhabdomyoblasts. The vagina is the most common site, but it can also occur, although rarely, in the cervix or uterine fundus.
View Article and Find Full Text PDFImplication of IL-12A, IL-12B, IL-6, and TNF single-nucleotide polymorphisms in severity and susceptibility to COVID-19.
Int J Immunopathol Pharmacol
September 2024
Background: The Coronavirus Disease 2019 (COVID-19) pandemic has led to significant global morbidity and mortality. Understanding the genetic factors that influence disease outcomes can provide critical insights into pathogenesis and potential therapeutic targets.
Objective: This study aimed to investigate the potential correlation between single nucleotide polymorphisms (SNPs) in , , , and genes and the severity as well as susceptibility to COVID-19 among Moroccan patients.
Objectives: The present study aimed to evaluate the frequencies of , and mutations and their possible associations with clinicopathological features in 249 Moroccan patients with colorectal cancer (CRC).
Methods: A retrospective investigation of a cohort of formalin-fixed paraffin-embedded tissues of 249 patients with CRC was screened for // mutations using Idylla™ technology and pyrosequencing.
Results: , and mutations were revealed in 46.