[Individual differences in the reactions to acute stress related to behavioral type. Resistance (predisposition) to behavioral and sleep disorders].

Resistance (predisposition) to behavior and sleep disturbances after acute stress was studied in rats with different types of behavior in open field and forced swimming tests. The highest resistance to stress (the least alterations of behavior and sleep parameters) was found in rats with the active type of behavior, the least resistance to stress--in the middle group, and rats with the passive type of behavior held the intermediate position. The comparison of the present data with previously obtained results showed a positive correlation between the resistance to stress and the resistance to circulatory cerebral hypoxia induced by bilateral common carotid arteries occlusion.

[Effect of substance P on survival of rats after cerebral ischemia: the effect depends on behavior type].

In rats with different behaviour types in tests of "open field" and "forced swimming", influence of intraperitoneal administration of P-substance (PC) neuropeptide to survival and structural-metabolic changes in brain after double-sided ligating of carotid arteries. It was established that PC exerts different influence on stability to circulating cerebral hypoxia according to behaviour types: it increases stability in rats with passive behaviour type, decrease stability in rats with active behaviour type and does not influence on rats with middle behaviour type. Results shows the necessity of individual approach to peptide use with the view to increase stabilization to cerebral ischemia.