Publications by authors named "I A Kleidona"

Introduction: Results from randomized controlled trials of upadacitinib, a Janus kinase (JAK) inhibitor, have led to its approval for the treatment of moderate-to-severe atopic dermatitis (AD) in patients aged ≥ 12 years. The aim of this study was to report the effectiveness and safety of upadacitinib in real-world settings over a period of 96 weeks.

Methods: This retrospective study included all patients treated with upadacitinib at our centre between April 2022 and September 2024.

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Article Synopsis
  • Previous studies have shown a connection between inflammatory skin diseases and mental health issues, particularly neuroticism, but the effects of specific neuroticism traits were not well studied.
  • This research used Mendelian randomization to analyze genetic data from psoriasis and atopic dermatitis, finding that psoriasis is associated with increased worry, while atopic dermatitis relates to elevated stress levels.
  • The results indicate opportunities for future treatments that could help alleviate stress and worry in patients with inflammatory skin diseases.
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Background: Neck aesthetics is an essential feature for a youthful attractive appearance. Deep neck surgery involving partial resection of the submandibular gland (SMG) has been a controversial issue in aesthetic surgery given its challenging technique and potential risks. The aim of this review is to evaluate the safety and efficacy of partial SMG resection in patients undergoing aesthetic neck surgery.

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